Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Urinary cytology in multiple myeloma

Patil S, Schwarer A, McLean C

(2008), Cytopathology, 19(2), 130-1

Expression and purification of the minor histocompatibility antigen, HA-1H generated in Escherichia coli

Etto TL, Stewart LA, Nguyen TH, Williamson NA, Purcell AW, Schwarer AP

(2007), Protein Expr Purif, 54(1), 176-82

Development of fatal bortezomib induced acute lung injury despite concurrent therapy with high-dose dexamethasone

Chew E, Filshie R, Wei A

(2007), Leuk Lymphoma, 48(1), 212-3

Rituximab responsive immune thrombocytopenic purpura in an adult with underlying autoimmune lymphoproliferative syndrome due to a splice-site mutation (IVS7+2T>C) affecting the Fas gene

Wei A, Cowie T

(2007), Eur J Haematol, 79(4), 363-6

Mouse serpins and transgenic studies

Askew DJ, Couglin P, Bird PI

(2007), In: Silverman GA, Lomas DA (eds). Chapter 4. Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity. World Scientific, Singapore, 101-29

Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis

Vandendries ER, Hamilton JR, Coughlin SR, Furie B, Furie BC

(2007), Proc Natl Acad Sci USA, 104(1), 288-92

Pilot study of an outpatient-based approach for advanced lymphoma using vinorelbine, gemcitabine and filgrastim

Spencer A, Reed K, Arthur C

(2007), Intern Med J, 37(11), 760-6

A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation

Slavin MA, Grigg AP, Schwarer AP, Szer J, Spencer A, Sainani A, Thursky KA, Roberts AW

(2007), Bone Marrow Transplant, 40(2), 157-63

PKC412 demonstrates JNK-dependent activity against human multiple myeloma cells

Sharkey J, Khong T, Spencer A

(2007), Blood, 109(4), 1712-9

Identification of a unique co-operative phosphoinositide 3-kinase signalling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets

Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S,Mulchandani M, Anderson K, Kauffenstein G, Rewcastle GW, Kendall J, Gachet C, Salem HH, Jackson SP

(2007), J Biol Chem, 282(39), 28648-58

Molecular characterization of centerin, a germinal centre cell serpin

Paterson MA, Horvath AJ, Pike RN, Coughlin PB

(2007), Biochem J, 405(3), 489-94

Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression

Orlowski RZ, Nagler A, Sonneveld P, Bladé J, Hajek R, Spencer A, San Miguel J, Robak T, Dmoszynska A, Horvath N, Spicka I, Sutherland HJ, Suvorov AN, Zhuang SH, Parekh T, Xiu L, Yuan Z, Rackoff W, Harousseau JL

(2007), J Clin Oncol, 25(25), 3892-901

Fibrinolysis, inflammation, and regulation of the plasminogen activating system

Medcalf RL

(2007), J Thromb Haemost, 5 (Suppl 1), 132-42

Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation

Maxwell MJ, Westein E, Nesbitt WS, Giuliano S, Dopheide SM, Jackson SP

(2007), Blood, 109(2), 566-76

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma

Lindemann RK, Newbold A, Whitecross KF, Cluse LA, Frew AJ, Ellis L, Williams S, Wiegmans AP, Dear AE, Scott CL, Pellegrini M, Wei A, Richon VM, Marks PA, Lowe SW, Smyth MJ, Johnstone RW

(2007), Proc Natl Acad Sci USA, 104(19), 8071-6

Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform

Kim S, Garcia A, Jackson SP, Kunapuli SP

(2007), Blood, 110(13), 4206-13

Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110alpha inhibitors

Kendall JD, Rewcastle GW, Frederick R, Mawson C, Denny WA, Marshall ES, Baguley BC, Chaussade C, Jackson SP, Shepherd PR

(2007), Bioorg Med Chem, 15(24), 7677-87

The growing complexity of platelet aggregation

Jackson SP

(2007), Blood, 109(12), 5087-95

Are Erk, Btk, and PECAM-1 major players in GPIb signaling? The challenge of unraveling signaling events downstream of platelet GPIb

Jackson SP, Cranmer S, Mangin P, Yuan Y

(2007), Blood, 109(2), 846-7

Differential regulation of adapter proteins Dok2 and Dok1 in platelets, leading to an association of Dok2 with integrin alphaIIbbeta3

Hughan SC, Watson SP

(2007), J Thromb Haemost, 5(2), 387-94

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