Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism

Roche M, Jakobsen MR, Sterjovski J, Ellett A, Posta F, Lee B, Jubb B, Westby M, Lewin SR, Ramsland PA, Churchill MJ, Gorry PR

(2011), J Virol, 85(9), 4330-42

HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry

Roche M, Jakobsen MR, Ellett A, Salimiseyedabad H, Jubb B, Westby M, Lee B, Lewin SR, Churchill MJ, Gorry PR

(2011), Retrovirology, 8, 89

Clinical predictors of immune reconstitution following combination antiretroviral therapy in patients from the Australian HIV Observational Database

Rajasuriar R, Gouillou M, Spelman T, Read T, Hoy J, Law M, Cameron PU, Petoumenos K, Lewin SR

(2011), PLoS One, 6(6), e20713

HIV seroconversions among male non-occupational post-exposure prophylaxis service users: a data linkage study

Pierce AB, Yohannes K, Guy R, Watson KM, Armishaw J, Price B, Hoy JF, Wright EJ, Stoové MA

(2011), Sex Health, 8(2), 179-83

Design issues in a randomized controlled trial of a pre-emptive versus empiric antifungal strategy for invasive aspergillosis in patients with high-risk hematologic malignancies

Morrissey CO, Chen SC, Sorrell TC, Bradstock KF, Szer J, Halliday CL, Gilroy NM, Schwarer AP, Slavin MA

(2011), Leuk Lymphoma, 52(2), 179-93

Antibody and B-cell responses may control circulating lipopolysaccharide in patients with HIV infection

Lim A, Amini A, D'Orsogna LJ, Rajasuriar R, Kramski M, Lewin SR, Purcell DF, Price P, French MA

(2011), AIDS, 25(11), 1379-83

Neurobehavioral effects in HIV-positive individuals receiving highly active antiretroviral therapy (HAART) in Gaborone, Botswana

Lawler K, Jeremiah K, Mosepele M, Ratcliffe SJ, Cherry C, Seloilwe E, Steenhoff AP

(2011), PLoS One, 6(2), e17233

Novel sensitive real-time PCR for quantification of bacterial 16S rRNA genes in plasma of HIV-infected patients as a marker for microbial translocation

Kramski M, Gaeguta AJ, Lichtfuss GF, Rajasuriar R, Crowe SM, French MA, Lewin SR, Center RJ, Purcell DF

(2011), J Clin Microbiol, 49(10), 3691-3

The role of naïve T-cells in HIV-1 pathogenesis: an emerging key player

Khoury G, Rajasuriar R, Cameron PU, Lewin SR

(2011), Clin Immunol, 141(3), 253-67

Increased intrahepatic apoptosis but reduced immune activation in HIV-HBV co-infected patients with advanced immunosuppression

Iser DM, Avihingsanon A, Wisedopas N, Thompson AJ, Boyd A, Matthews GV, Locarnini SA, Slavin J, Desmond PV, Lewin SR

(2011), AIDS, 25(2), 197-205

Outcomes from the first assisted reproduction program for HIV-serodiscordant couples in Australia

Giles ML, Barak S, Baker G, Perna S, Tabrizi S, Greengrass V, Bourne H, Clarke GN, Peak SA, Hoy JF, Foster P, Knight RL; CVI Study Group

(2011), Med J Aust, 195(10), 599-601

CD4+ T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4+ T cells

Fernandez S, Tanaskovic S, Helbig K, Rajasuriar R, Kramski M, Murray JM, Beard M, Purcell D, Lewin SR, Price P, French MA

(2011), J Infect Dis, 204(12), 1927-35

Thymic plasmacytoid dendritic cells are susceptible to productive HIV-1 infection and efficiently transfer R5 HIV-1 to thymocytes in vitro

Evans VA, Lal L, Akkina R, Solomon A, Wright E, Lewin SR, Cameron PU

(2011), Retrovirology, 8, 43

Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy

Doyle JS, Campbell E, Fuller A, Spelman DW, Cameron R, Malham G, Gin D, Lewin SR

(2011), J Neurosurg, 114(2), 458-62

A longitudinal study of the effects of ART on plasma chemokine levels in Malaysian HIV patients

Chew CS, Cherry CL, Kamarulzaman A, Yien TH, Aghafar Z, Price P

(2011), Dis Markers, 31(5), 303-9

Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients

Chew CS, Cherry CL, Imran D, Yunihastuti E, Kamarulzaman A, Varna S, Ismail R, Phipps M, Aghafar Z, Gut I, Price P

(2011), Tissue Antigens, 77(2), 126-30

Symptomatic and asymptomatic early neurosyphilis in HIV-infected men who have sex with men: a retrospective case series from 2000 to 2007

Chang CC, Leslie DE, Spelman D, Chua K, Fairley CK, Street A, Crowe SM, Hoy JF

(2011), Sex Health, 8(2), 207-13

Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4+ T-cell response: a randomized controlled trial

Byakwaga H, Kelly M, Purcell DF, French MA, Amin J, Lewin SR, Haskelberg H, Kelleher AD, Garsia R, Boyd MA, Cooper DA, Emery S; CORAL Study Group

(2011), J Infect Dis, 204(10), 1532-40

Factors associated with elevated ALT in an international HIV/HBV co-infected cohort on long-term HAART

Audsley J, Seaberg EC, Sasadeusz J, Matthews GV, Avihingsanon A, Ruxrungtham K, Fairley K, Finlayson R, Hwang HS, Littlejohn M, Locarnini S, Dore GJ, Thio CL, Lewin SR

(2011), PLoS One, 6(11), e26482

Non-occupational post-exposure prophylaxis in Victoria, Australia: responding to high rates of re-presentation and low rates of follow-up

Armishaw J, Hoy JF, Watson KM, Wright EJ, Price BG, Pierce AB

(2011), Int J STD AIDS, 22(12), 714-8

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