A/Prof James Shaw
Associate Professor James Shaw is one of the Deputy Directors and Head of Education and Training in Cardiology, and has held this position since 2014.
He is an interventional cardiologist with a specific interest in the pathophysiology of atherosclerosis both in the coronary and non coronary vascular beds. He is involved in inpatient and outpatient care and partakes in the transthoracic and transoesophageal echocardiogram reporting roster. He is a visiting cardiologist to Sandringham Hospital and to the Bairnsdale Regional health service where he provides outpatient services on a regular basis.
Following completion of his cardiology training in 1997, he undertook a PhD under the supervision of Professor Dart at the Baker Heart and Diabetes Institute and his thesis titled “Mechanisms of Plaque Stability in Coronary Artery Disease” was successfully completed in 2001. Following this he spent 2.5 years at Massachusetts General Hospital and the Brigham and Womens Hospital in Boston completing further clinical and research training in coronary and non coronary interventional work.
In 2004 he returned to Melbourne where he helped establish The Alfred Minimally Invasive Vascular Centre which focuses on endovascular intervention for non coronary atherosclerotic disease. The research interests of Dr Shaw’s group are aligned to the clinical interests and involve active collaboration between various laboratories in the Baker Institute and the clinical department of The Alfred.
He has successfully supervised students in their B Med Science and BSci (hons) projects and is actively involved in registrar supervision and training as well as helping train interventional cardiology fellows many of whom have gone on to gain senior positions.
Dr Shaw has published over 50 peer reviewed manuscripts and has been the Principal Investigator in numerous clinical trials in including the IMPROVE-IT, COMPASS and the ODYSSEY Outcomes studies.
Selected papers are:
- Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI.
Lukito P, Wong A, Jing J, Arthur JF, Marasco SF, Murphy DA, Bergin PJ, Shaw JA, Collecutt M, Andrews RK, Gardiner EE, Davis AK.
J Thromb Haemost. 2016 Nov;14(11):2253-2260 - Circulating vitamin D levels are associated with the presence and severity of coronary artery disease but not peripheral arterial disease in patients undergoing coronary angiography
Liew JY, Sasha SR, Ngu PJ, Warren JL, Wark J, Dart AM, Shaw JA
Nutr Metab Cardiovasc Dis. 2015 Mar;25(3):274-9 - Diffuse myocardial fibrosis evaluated by post-contrast t1 mapping correlates with left ventricular stiffness.
Ellims AH, Shaw JA, Stub D, Iles LM, Hare JL, Slavin GS, Kaye DM, Taylor AJ.
J Am Coll Cardiol. 2014 Mar 25;63(11):1112-8 - Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis
Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N
Nat Med. 2013 May;19(5):586-94. - Randomised Double Blind Placebo Controlled Crossover Study To Determine The Effects of Esomeprazole on the Inhibition of Platelet Function by Clopidogrel
Fernando H, Bassler N, Habersberger J, Sheffield L, Sharma R, Dart AM, Peter K, Shaw JA.
Journal of Thrombosis and Haemostasis 2011 Aug;9(8):1582-9.